Telomeres and Telomerase in Cancer (Cancer Drug Discovery and Development)

Keiko Hiyama, "Telomeres and Telomerase in Cancer (Cancer Drug Discovery and Development)"
Humana Press | 2009-02-27 | ISBN: 1603273069 | 380 pages | PDF | 13,6 MB

Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.

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Immunity Against Mucosal Pathogens

Michael Vajdy "Immunity Against Mucosal Pathogens"
Springer | 2008-08-01 | ISBN: 1402084110 | 540 pages | PDF | 12 MB

Surprisingly what separates us from the open environment all around us sometimes is a single layer of epithelial cells. It is at these seemingly fragile sites that most pathogens, including HIV, influenza, emerging and biodefense agents, gain access to our inside milieu. While there are major similarities between the cells and the immune responses generated at the mucosal membranes of the gastrointestinal and respiratory tracts together with the genitourinary tract, there are also important differences. Knowledge of these differences and similarities is required in order to understand the interactions between us, as the host, and the pathogens that attack through each tract, and how our immune system reacts to each of them. Whether we want to devise rational prophylactic or therapeutic vaccines or treatments to either prevent or treat mucosal infections we must acquire such knowledge. This is the rationale behind putting this book together.

This book will provide the readers in the areas of vaccinology, virology, bacteriology, epidemiology, immunology and mucosal immunology within academia (undergraduate, graduate, post doctoral fellows and professors), as well as preclinical and clinical scientists in vaccine and drug industries a thorough appreciation of the mucosal immune system and its importance in protecting humans against mucosal pathogens.


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Nature Medicine - February 2009

Nature Medicine - February 2009
English | 102 pages | PDF | 13.16 MB

Nature Medicine is the premier journal for biomedical research. Respected internationally for the quality of its papers on areas ranging from infectious disease to cancer and neurodegeneration, Nature Medicine aims to bridge the gap between basic research and medical advances and is consistently ranked the number one journal by the Institute of Scientific Investigation in the Medicine, Research and Experimental category.


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Nature Medicine - January 2009

Nature Medicine - January 2009
English | 124 pages | PDF | 13.65 MB

Nature Medicine is the premier journal for biomedical research. Respected internationally for the quality of its papers on areas ranging from infectious disease to cancer and neurodegeneration, Nature Medicine aims to bridge the gap between basic research and medical advances and is consistently ranked the number one journal by the Institute of Scientific Investigation in the Medicine, Research and Experimental category.


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Hernienchirurgie: Klinische Strategien und perioperatives Management

J.-P. Ritz, H.J. Buhr, "Hernienchirurgie: Klinische Strategien und perioperatives Management"
Springer | 2005-11-03 | ISBN: 3540277242 | 157 pages | PDF | 8,8 MB

Auf der Suche nach der besten Methode
Die Diskussion um das beste, komplikations- und rezidivärmste Verfahren zur Operation abdominaler Hernien wird kontinuierlich geführt: Ist ein konventionelles oder ein spannungsfreies Operationsverfahren vorzuziehen? Welches Mesh-Material bringt die besten Ergebnisse? Wie sieht das optimale peri- und postoperative Management aus?
Den aktuellen Stand der modernen Hernienchirurgie finden Sie in diesem Buch zusammengefasst: Indikation und Technik der unterschiedlichen Verfahren - Bewertung alloplastischer Materialien - Behandlung komplexer Hernien - postoperative Behandlung und Nachsorge.
Das Praxiswissen für den klinischen Alltag!

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Novel Enzyme Technology for Food Applications (2007)

Novel Enzyme Technology for Food Applications
Publisher: Woodhead Publishing | English | ISBN:1845691326 | 336 pages | 2007 | PDF | 2 Mb

Description: The food industry is constantly seeking advanced technologies to meet consumer demand for nutritionally balanced food products. Enzymes are a useful biotechnological processing tool whose action can be controlled in the food matrix to produce higher quality products. Written by an international team of contributors, Novel enzyme technology for food applications reviews the latest advanced methods to develop specific enzymes and their applications. Part 1 discusses fundamental aspects of industrial enzyme technology. Chapters cover the discovery, improvement and production of enzymes as well as consumer attitudes towards the technology. Chapters in Part 2 discuss enzyme technology for specific food applications such as textural improvement, protein-based fat replacers, flavour enhancers, and health-functional carbohydrates.

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Atlas of Urogynecological Endoscopy (2007)

Atlas of Urogynecological Endoscopy
Publisher: Informa Healthcare | English | ISBN:184184540X | 208 pages | Data: 2007 | PDF | 18 Mb

Description: The study of gynecology and pelvic floor disorders is a rapidly developing area for gynecologists around the world, and, moreover, an essential aspect to the diagnosis and treatment of pelvic floor disorders is a need for expertise in cystourethroscopy to accurately diagnose conditions of the lower urinary tract that frequently present to the gynecologists. However, gynecologists have little training or expertise in the use of cystourethroscopy and therefore often do not feel comfortable in performing this procedure or distinguishing what is normal from what is abnormal. An excellent guide for educating gynecologists in endoscopy of the urinary tract, this highly illustrated text addresses this need and provides readers with a full understanding of the equipment that is used, how it is used, and the conditions of the lower urinary tract they may find in the treatment of pelvic disorders.

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